Targeting a common collaborator in cancer development - P13K inhibitor (short abstract) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Sunday, September 12, 2010

Targeting a common collaborator in cancer development - P13K inhibitor (short abstract)



Abstract

In this issue of Science Translational Medicine, Wallin et al. have identified a subset of breast and ovarian cancer cell lines that show synergistic response to the combination of doxorubicin and GDC-0941, a class IA phosphatidylinositol 3-kinase (PI3K) inhibitor. Here, we discuss the potential implications of these data on the clinical development of PI3K pathway inhibitors as cancer therapeutics.

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