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".....Regarding the question of gene-environment
interactions, lead author Ruth Travis, MD, PhD, adds that “Results from
this study suggest that common genetic and environmental factors
(reproductive and lifestyle factors) act independently on breast cancer
risk, so regardless of common inherited genetic variation, a woman can
still reduce her risk by modifying her lifestyle, for example by
maintaining a healthy body weight and limiting alcohol intake.”
The
absence of interactions means that priorities for risk-reducing
strategies are similar for most women (for example, being based on known
risks associated with lifestyle and reproductive factors) regardless of
the common genetic risk factors for the disease, she says. Dr. Travis
is an epidemiologist, research fellow, and senior scientist in the
cancer epidemiology unit at Oxford University....."
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