Editorial: New guidelines for early detection of ovarian cancer : The Lancet

"....NICE advises primary care professionals to measure serum concentrations of the protein CA125 if a woman (especially if older than 50 years) presents on a persistent or frequent basis with abdominal distension, feeling full or loss of appetite, pelvic or abdominal pain, or increased urinary frequency. If the blood test is positive, an ultrasound of the abdomen or pelvis should be done and, if ovarian cancer is suggested, the woman should be referred to a specialist...."