Access : Open-label feasibility study of pazopanib, carboplatin, and paclitaxel in women with newly diagnosed, untreated, gynaecologic tumours: a phase I|[sol]|II trial of the AGO study group : British Journal of Cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, January 16, 2012

Access : Open-label feasibility study of pazopanib, carboplatin, and paclitaxel in women with newly diagnosed, untreated, gynaecologic tumours: a phase I|[sol]|II trial of the AGO study group : British Journal of Cancer



 "Severe myelotoxicity was reported in 6 of 12 patients."

Conclusion:
Combining either 800 or 400mg per day pazopanib with standard carboplatin/paclitaxel chemotherapy is not a feasible treatment option.

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