PET/CT imaging in gynecologic malignancies: A critical overview of its clinical impact and our retrospective single center analysis 10.1016/j.critrevonc.2011.10.002 : Critical Reviews in Oncology

  A growing body of evidence defines PET/CT as one of the most powerful tools for tumor, nodal and metastasis (TNM) cancer staging both in pre-treatment and in post treatment follow-up settings.

At any phase of cancer evaluation, detection of metastasis represents one of the most critical impediments to the cure of tumor; traditional diagnostic imaging modalities, such as computed tomography (CT), are frequently found to inadequately stage the tumor, based on subsequent outcomes.. ...

Highlights

► FDG-PET/CT is a valid instrument for the detection of recurrent or metastatic gynaecologic tumours.
► Evidence corroborates FDG-PET/CT's role in ovarian cancer in monitoring response to chemotherapy.
► In uterine cervical carcinoma, FDG-PET/CT is more sensitive than MRI for detecting nodal metastases.
► Retrospective analysis of 116 patients showed FDG-PET/CT was principally useful in the setting of suspected recurrence.