abstract: Distinct Subpopulations of Epithelial Ovarian Cancer Cells Can Differentially Induce Macrophages and T Regulatory Cells Toward a Pro-Tumor Phenotyp Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, February 06, 2012

abstract: Distinct Subpopulations of Epithelial Ovarian Cancer Cells Can Differentially Induce Macrophages and T Regulatory Cells Toward a Pro-Tumor Phenotyp



Problem  Presence of immune infiltrates in the tumor does not always correlate with an anti-tumoral immune response. (eg. vaccine therapies...)
Conclusion 
We demonstrate that each ovarian cancer cell subpopulation can induce a unique phenotype of macrophages and T cells, both associated with tumor-supportive function.

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