abstract: Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies : The Lancet Oncology

Background

Endometriosis is a risk factor for epithelial ovarian cancer; however, whether this risk extends to all invasive histological subtypes or borderline tumours is not clear. We undertook an international collaborative study to assess the association between endometriosis and histological subtypes of ovarian cancer.

 Interpretation

Clinicians should be aware of the increased risk of specific subtypes of ovarian cancer (clear cell, endometrioid) in women with endometriosis. Future efforts should focus on understanding the mechanisms that might lead to malignant transformation of endometriosis so as to help identify subsets of women at increased risk of ovarian cancer.