France: Search for Predictors of Therapeutic Response in Ovarian Carcinoma - Full Text View - ClinicalTrials.gov Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Saturday, February 25, 2012

France: Search for Predictors of Therapeutic Response in Ovarian Carcinoma - Full Text View - ClinicalTrials.gov



Search for Predictors of Therapeutic Response in Ovarian Carcinoma (miRSa)
This study is currently recruiting participants.
Verified February 2012 by Centre Francois Baclesse

First Received on July 8, 2011. Last Updated on February 23, 2012 History of Changes

Further study details as provided by Centre Francois Baclesse:

Primary Outcome Measures:
  • search for predictors of response to chemotherapy [ Time Frame: 12 months after beginning treatment ] [ Designated as safety issue: No ]
    the search for predictors of response to chemotherapy in patients with carcinoma of the ovary, the fallopian tube or peritoneal serous-type advanced by using (i) the miRNA profile of serum before treatment with chemotherapy and (ii) the identification of polymorphisms or SNPs (Single Nucleotide polymorphism) in particular genes involved in the metabolism of chemotherapy agents


Secondary Outcome Measures:
  • profiling miRNA expression [ Time Frame: 1 month ] [ Designated as safety issue: No ]
    - Characterization of the response to treatment with profiling miRNA expression after the first course of chemotherapy in patients with carcinoma of the ovary, the fallopian tube or peritoneal serous-type advanced

  • study of changes in serum miRNA expression [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    - The study of changes in serum miRNA expression identified as predictive of tumor response during chemotherapy treatment.
 

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