Dr Maurie Markman: Clinical Oncology News - A Provocative Intersection: Rare cancers, “approved” anti-neoplastics and preclinical models Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Tuesday, March 20, 2012

Dr Maurie Markman: Clinical Oncology News - A Provocative Intersection: Rare cancers, “approved” anti-neoplastics and preclinical models



Clinical Oncology News - A Provocative Intersection: Rare cancers, “approved” anti-neoplastics and preclinical models

"Preclinical results describing a novel approach to the treatment of an uncommon malignant condition raise a provocative question: How, in the current increasingly rigid “guideline-based” era of cancer management, can such observations ever leave the realm of the laboratory to be examined in the clinic? And can a rational approach to this highly relevant dilemma be devised?
Primary mucinous tumors comprise a very small proportion (<5%) of morphologic subtypes found in patients with advanced epithelial ovarian cancer......."

"....One might even argue that the outcome of such individual non-investigative experiences be posted in an easily identified, well-organized, condition-specific online database (with absolutely no accompanying patient-specific identifiers), so the oncology community would be aware of any clinically beneficial effects observed if colleagues had previously attempted to employ this novel approach in an individual patient with a metastatic mucinous ovarian cancer.....

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