abstract: Topoisomerase 1 Inhibitors and Cancer Therapy Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, April 25, 2012

abstract: Topoisomerase 1 Inhibitors and Cancer Therapy



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Topoisomerase 1 Inhibitors and Cancer Therapy

 Abstract: "Topoisomerase 1 inhibitors cure human cancer xenografts in animal models, more so than most other chemotherapy agents. However, their activity in patients with cancer is modest. Ongoing research is studying the optimal analogues that could reproduce animal data in the cancer population. This article analyzes the clinical research with topoisomerase 1 inhibitors in ovarian cancer."

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