Review of epidemiologic studies of dietary acrylamide intake and the risk of cancer.

Review of epidemiologic studies of dietary acrylamide intake and the risk of cancer.:

Eur J Cancer Prev. 2012 Apr 8;

Abstract
Hypothesized associations between dietary acrylamide intake and cancer have been evaluated in more than 15 epidemiologic studies examining almost every major cancer site. We have critically reviewed the epidemiologic studies of estimated dietary acrylamide exposure and cancer.....

In conclusion, epidemiologic studies of dietary acrylamide intake have failed to demonstrate an increased risk of cancer. In fact, the sporadically and slightly increased and decreased risk ratios reported in more than two dozen papers examined in this review strongly suggest the pattern one would expect to find for a true null association over the course of a series of trials. Therefore, continued epidemiologic investigation of acrylamide and cancer risk appears to be a misguided research priority.