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Editorial: JAMA Network Lynch Syndrome in Patients With Colorectal Cancer Finding the Needle in the Haystack
Editorial
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October 17, 2012
JAMA. 2012;308(15):1581-1583. doi:10.1001/jama.2012.14171.
"Identification
of individuals at increased risk of hereditary cancer allows for the
possibility of screening and early cancer detection, possibly resulting
in decreased disease-specific mortality, and is the justification for
germline genetic testing for specific cancer risk alleles. However,
factors of prevalence and age-specific penetrance, effectiveness and
invasiveness of screening procedures, and efficacy of early detection
influence the potential benefit of such an approach."
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