Current delays in setting-up investigator-driven randomised controlled trials: the MRC ICON8 experience

Current delays in setting-up investigator-driven randomised controlled trials: the MRC ICON8 experience

Conclusion

The time taken to establish clinical trials is still unacceptably long despite recent introduction of the 70-day benchmark for time from commencing R&D checks to first patient recruited. Obtaining NHS R&D approval accounts for the majority but later delays also occur. Implementation of proposed reforms to the research governance process is required.