open access: Paraneoplastic cerebellar degeneration associated with ovarian cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Thursday, November 08, 2012

open access: Paraneoplastic cerebellar degeneration associated with ovarian cancer



Paraneoplastic cerebellar degeneration associated with ovarian cancer


Published online on:
Wednesday, November 7, 2012

Doi:
10.3892/ol.2012.1016

Abstract:
Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64‑year‑old woman who developed PCD symptoms, associated with high levels of anti‑Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.

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