open access: Stratifying Risk of Urinary Tract Malignant Tumors in Patients With Asymptomatic Microscopic Hematuria (Lynch Syndrome patients)

 Blogger's Note: this research article did not include any references to Lynch Syndrome nor past history of any cancer/s; a large portion of the included references were >10 yrs

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Stratifying Risk of Urinary Tract Malignant Tumors in Patients With Asymptomatic Microscopic Hematuria

"...For malignant findings, the incidence of renal cancer was extremely low in our study (0.3%), and no ureteral or transitional cell carcinomas of the upper urinary tract were identified in either cohort....." 

" This study has several potential limitations that should be taken into consideration when interpreting our results. Not all urologists participated in the data collection; therefore, not all patients who may have undergone microhematuria evaluation were included in either cohort, and these patients may be systematically different from those who were included. Data were entered for only 50% of patients who underwent cystoscopy for microhematuria during the period. The similarity in cancer diagnosis rates among those followed up according to plan vs not, however, suggests that this likely played only a small role....."

Conclusion 

These data suggest that microscopic hematuria is an unreliable indicator of urinary tract malignant tumors. Patients with microscopic hematuria younger than 50 years and with no history of gross hematuria may not benefit from further evaluation and therefore could avoid unnecessary risk from radiation exposure and invasive endoscopy. These findings may be used to simplify referral guidelines for evaluation in asymptomatic patients with microscopic hematuria and reduce the number of unnecessary evaluations.