BMC Cancer | open access First description of an acinic cell carcinoma of the breast in a BRCA1 mutation carrier: a case report

BMC Cancer | Abstract | First description of an acinic cell carcinoma of the breast in a BRCA1 mutation carrier: a case report

 Background

Acinic cell carcinoma (ACC) is a rare malignant epithelial neoplasm characterized by the presence of malignant tubular acinar exocrine gland structures. Diagnosis is generally made in salivary glands and in the pancreas. ACC of the breast has been reported in few cases only. Carriers of inherited mutations in the BRCA1 gene are prone to the development of breast cancer, mainly invasive ductal or medullary type carcinomas. We describe for the first time a BRCA1 mutation carrier with a diagnosis of ACC of the breast.....