3 articles - genome - BRCA1/BRCA2/breast cancer associations in Asians

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BRCA1 mutation carriers
BRCA1 mutation carriers are at increased risk for both breast and
ovarian cancers.....

BRCA2 mutation carriers
A previous study from the Consortium of Investigators of Modifiers
of BRCA1/2 (CIMBA) reported a genome-wide association study
(GWAS) for breast cancer risk in BRCA2 mutation carriers (PLoS Genet.
6, e1001183, 2010), identifying only known loci previously associated
with breast cancer risk in the general population. Kenneth Offit and
colleagues now report an extended replication, including genotyping
using the iCOGS array, of 3,881 BRCA2 mutation carriers with breast
cancer and 4,330 without breast cancer from CIMBA...

Breast cancer associations in east Asians
To extend findings of breast cancer association studies that have primarily been conducted in European-ancestry populations, Wei Zheng
and colleagues systematically examined the association of known
breast cancer susceptibility loci in east Asian women....