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1) Wiki
2) Medline
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Abstract
Infection. 2013 Mar 15. [Epub ahead of print]
The
coexistence of clostridial gas gangrene and a gynecologic malignancy is
extremely rare, with very few cases involving ovarian cancer. A patient
originally presented to our gynecologic oncology service with stage IV
ovarian cancer; she underwent a diagnostic laparoscopy and neoadjuvant
chemotherapy. On postoperative day 6, the patient developed severe
abdominal pain, nausea, and emesis, suggestive of a bowel perforation.
Further evaluation confirmed that her symptoms were attributed to Clostridium perfringens-related gas gangrene. Despite immediate surgical intervention, the patient succumbed to her disease. Clostridial gas gangrene is associated with an extremely high mortality rate. Therefore, accurate detection and prompt management are indispensable to ensuring a favorable patient outcome.
Further evaluation confirmed that her symptoms were attributed to Clostridium perfringens-related gas gangrene. Despite immediate surgical intervention, the patient succumbed to her disease. Clostridial gas gangrene is associated with an extremely high mortality rate. Therefore, accurate detection and prompt management are indispensable to ensuring a favorable patient outcome.
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