Elevated Risk of Prostate Cancer Among Men With Lynch Syndrome

abstract

Conclusion The cumulative lifetime risk of prostate cancer in individuals with LS is two-fold higher than in the general population and is slightly higher in carriers diagnosed before age 60 years (HR, 2.48; 95% CI, 1.34 to 4.59). These estimates are clinically valuable to quantify risk for both patients and providers.

Footnotes (not available unless paid subscriber)

• See accompanying article doi: 10.1200/JCO.2012.48.4667