Genetics May Be Tied to Breast Cancer Risk in Unexpected Ways - MedicineNet

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"...."Currently, three drugs can be used to prevent breast cancer in women who are at extremely high risk for the disease," study co-author Dr. Seema Khan, said in a journal release. "However, these drugs prevent only breast cancers that are sensitive to hormones, commonly referred to as estrogen receptor-positive breast cancers. They do not prevent breast cancers that are insensitive to hormones, or estrogen receptor-negative breast cancers."
"We should not expose women at risk for hormone-insensitive breast cancer to the side effects of preventive medications that we know will not work for them," added Khan, who is co-leader of the Breast Cancer Program at Northwestern University, in Chicago. "Moreover, if we knew who these women were, we could focus on them in terms of designing new studies to find a solution for preventing hormone-insensitive cancer."....