numerous research articles: ovarian cancer search

Scholar Alert: [ intitle:"ovarian cancer" ]; Articles excluding patents

A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth.

DC Marchion, E Bicaku, Y Xiong, NB Zgheib… - Oncology reports, 2013

Elevated serum levels of hepatocyte growth factor (HGF) and high tumor expression of c-Met
are both indicators of poor overall survival from ovarian cancer (OVCA). In the present study,
we evaluated the role of the HGF signaling pathway in OVCA cell line chemoresistance ...

Mirk/dyrk1B Kinase in Ovarian Cancer

E Friedman - International Journal of Molecular Sciences, 2013

Abstract: Mirk/dyrk1B kinase is expressed in about 75% of resected human ovarian cancers
and in most ovarian cancer cell lines with amplification in the OVCAR3 line. Mirk (minibrain-
related kinase) is a member of the Minibrain/dyrk family of related serine/threonine ...

The incidence of PALB2 c. 3113G> A in women with a strong family history of breast and ovarian cancer attending familial cancer centres in Australia.

ZL Teo, SD Sawyer, PA James, G Mitchell, AH Trainer… - Familial cancer, 2013

The familial aggregation of breast cancer has been well-described with approximately 25%
of breast cancers attributable to inherited mutations in currently known breast cancer
susceptibility genes. PALB2 c. 3113G> A (p. Trp1038*) is a protein-truncating mutation ...

Immune escape of AKT overexpressing ovarian cancer cells.

JC Hahne, SR Meyer, S Gambaryan, U Walter, J Dietl… - International journal of …, 2013

Platinum-resistance is the most crucial problem for treatment of ovarian cancer. There is a
clinical need for new treatment strategies which overcome platinum resistance. As survival is
strongly influenced by immunological parameters, immunotherapeutic strategies appear ...

Folate-Conjugation to Polymeric Micelles via Boronic Acid Ester to Deliver Platinum Drugs to Ovarian Cancer Cell lines.

W Scarano, HT Duong, H Lu, PL De Souza… - Biomacromolecules, 2013

Abstract In this study, a novel technique was used for the reversible attachment of folic acid
on the surface of polymeric micelles for a tumor-specific drug delivery system. The reversible
conjugation is based on the interaction between phenylboronic acid (PBA) and dopamine ...

[HTML] Tumor Stress-Induced Phosphoprotein1 (STIP1) as a Prognostic Biomarker in Ovarian Cancer

A Chao, CH Lai, CL Tsai, S Hsueh, C Hsueh, CY Lin… - PloS one, 2013

Abstract Stress-induced phosphoprotein 1 (STIP1) has been recently identified as a
released biomarker in human ovarian cancer. In addition, STIP1 secreted by human ovarian
cancer cells has been shown to promote tumor cell proliferation by binding to ALK2 ( ...

The relationship between tumor size and stage in early versus advanced ovarian cancer

LE Horvath, T Werner, K Boucher, K Jones - Medical Hypotheses, 2013

Background Ovarian cancer has a different prognosis between early (I and II) and advanced
stage (III and IV). The mechanism of disease progression is unknown, but patients with
advanced disease may have a higher propensity for seeding of the abdominal cavity early ...

Icb-1 gene counteracts growth of ovarian cancer cell lines

O Treeck, S Schüler, J Häring, M Skrzypczak, C Lattrich… - Cancer Letters, 2013

Abstract Human gene icb-1 has been originally identified to be involved in differentiation
processes of cancer cells. To examine the function of icb-1 in ovarian cancer, we knocked
down its expression in three ovarian cancer cell lines and performed microarray-based ...

Effects of Sodium Valproate on the Growth of Human Ovarian Cancer Cell Line HO8910.

HC Yan, J Zhang - Asian Pacific journal of cancer prevention: APJCP, 2012

To explore a possible new treatment for human ovarian cancer, we studied the effects of
sodium valproate on the growth of the HO8910 human cell line. HO8910 cells were cultured
in vitro and treated with different concentrations of sodium valproate. Cell proliferation, cell ...

Identification of Cisplatin-Resistance Associated Genes through Proteomic Analysis of Human Ovarian Cancer Cells and a Cisplatin-resistant Subline.

J Zhou, YH Wei, MY Liao, Y Xiong, JL Li, HB Cai - Asian Pacific journal of cancer …, 2012

Chemoresistance to cancer therapy is a major obstacle to the effective treatment of human
cancers with cisplatin (DDP), but the mechanisms of cisplatin-resistance are not clear. In this
study, we established a cisplatin-resistant human ovarian cancer cell line (COC1/DDP) ...

Induction of apoptosis of ovarian cancer cells and influence on Fas-mediated apoptosis pathway by nanosecond pulsed electric fields].

R Xia, J Tang, X Zhao, F Guo, J Wang, C Yao - Sheng wu yi xue gong cheng xue za …, 2012

This paper is to investigate the apoptosis effect of ovarian cancer SKOV3 cells induced by
nanosecond plused electric fileds (nsPEFs) and to study its influence on Fas-mediated
apoptosis. SKOV3 cell were exposed to the 45kV/cm of field intensity, 30 pulses, and 50ns ...