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Blogger's Note: included gyn cancer patients; Harvard researchers
Open access
Background
Clinical interpretation of health related quality of life (HRQOL) scores is challenging.
The purpose of this analysis was to interpret score changes and identify minimal clinically
important differences (MCID) on the European Organization for Research and Treatment
of Cancer Quality of Life Questionnaire-Core 30 (QLQ-C30) before (T1) and during (T2)
cancer treatment.
"We also observed decreases in QLQ-C30 scores among patients reporting “about the same” in the SSQ for the PF and global QOL domains. This finding suggests a potential response shift in scoring of HRQOL. Response shift is known as the change in internal standards,
values, and the conceptualization of HRQOL after the start of cancer treatment [21]. Patients may report a better health condition even though their actual physical condition has deteriorated when they perceive a greater survival benefit from cancer treatment [21,22].
Further exploration and conceptual work are necessary to better understand the effect of response shift on patient-reported HRQOL scores."
values, and the conceptualization of HRQOL after the start of cancer treatment [21]. Patients may report a better health condition even though their actual physical condition has deteriorated when they perceive a greater survival benefit from cancer treatment [21,22].
Further exploration and conceptual work are necessary to better understand the effect of response shift on patient-reported HRQOL scores."
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