Promoter Methylation Status and Protein Expression of BRCA2 in Patients with Epithelial Ovarian Cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Saturday, March 16, 2013

Promoter Methylation Status and Protein Expression of BRCA2 in Patients with Epithelial Ovarian Cancer



pdf

"It has been proven that BRCA1 and BRCA2 methylation are altered in breast cancer. BRCA1 methylation status in ovarian cancer has been
examined, however the BRCA2 gene is under review."

"Based on our results and those of previous studies, it can be concluded that alteration in the methylation of BRCA2 may not be a risk factor
for ovarian cancer development in this studied population, and thus it is not an appropriate biomarker for the early diagnosis of ovarian cancer."

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