Burkitt’s Lymphoma Presented as Advanced Ovarian Cancer without Evidence of Lymphadenopathy: CT and MRI Findings

open access

The updated WHO Classification of Lymphoid Neoplasms (2008) identifies Burkitt’s lymphoma (BL) as a highly aggressive and fast growing mature B-cell neoplasm that often presents in extranodal sites or as an acute leukemia. Although the incidence of BL is low, accounting for only 1~2% of all lymphomas in western countries, it is one of the most common types of malignant tumors in children (endemic, sporadic) and immunocompromised hosts [1]. Involvement of the ovary by BL can be a manifestation of a systemic disease or, even more rarely, true primary ovarian lymphoma [2]. We present here the MRI and CT findings of a case of sporadic Burkitt’s lymphoma mimicking an ovarian cancer with associated bone involvement but without evidence of lymphadenopathy. A follow-up CT scan after 4 weeks, following one cycle of chemotherapy, was performed and showed a remarkable reduction of the ovarian lesions but not of the bone ones.

Case Report
We present a case of a 23-year-old nulliparous woman who was admitted to the hospital because of a two-month facial pain, increased abdominal circumference with constipation, pain to her lower left arm, excessive sweating, and weight loss. Abdominal ultrasound showed a large pelvic mass measuring 13 cm in diameter and a small amount of free fluid in the pelvis......