CoDP: predicting the impact of unclassified genetic variants in MSH6 by the combination of different properties of the protein (Lynch Syndrome)

Blogger's Note: of interest (technical) for Lynch Syndrome patients/dual primaries - ovarian/uterine and those with unclassifed variants/unknown significance; included are references regarding MSH6 etc

open access

Conclusion

In this paper, we provide a human curated data set for MSH6 missense variants, and CoDP, the prediction tool, which achieved better accuracy for predicting the impact of missense variants in MSH6 than any other known tools. CoDP is available at http://cib.cf.ocha.ac.jp/CoDP/.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.