Fungal Infections Associated with Contaminated Methylprednisolone Injections — Preliminary Report — NEJM

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"There has been no systematic surveillance in the United States for adverse events that occur after glucocorticoid injections for the treatment of chronic musculoskeletal pain, but infection is a known, although probably rare, risk documented in the medical literature.1-6 Infections that develop after a procedure are usually bacterial2,7-10; fungal infections are extremely rare.11-14 We present preliminary data on a multistate outbreak of fungal meningitis and other infections associated with injections of preservative-free methylprednisolone acetate that was purchased from a single compounding pharmacy and describe the initial public health response to the outbreak.....