Mediastinal involvement in ovarian cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, May 08, 2013

Mediastinal involvement in ovarian cancer



case report - abstract

Learning points

  • Ovarian cancer is the second most common gynaecological malignancy, being the leading cause of gynaecological cancer-related mortality.
  • Lymphatic spread and direct peritoneal tumour seeding are the most common metastatic routes of ovarian cancer.
  • Mediastinal involvement is rare in patients with ovarian cancer, yet possible. Mediastinal involvement is associated with advanced disease stage and poor prognosis. 

    Description

    A 57-year-old woman was diagnosed with serous papillary ovarian adenocarcinoma, for which she underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy and appendectomy (omentum, appendix and other organs other than left ovary were grossly normal). CT scan of the chest was done, which showed prevascular lymph node measuring up to 4.5 cm (figure 1). The lymph node was biopsied, which stained positive for cytokeratin 7 and Wilms tumor gene product (WT)-1, which consistent with metastatic ovarian adenocarcinoma..........

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