Study Shows Protein Complex May Play Role In Preventing Many Forms Of Cancer

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"......The researchers combined biochemical experiments with the data mining of 44 pre-existing studies to come to their conclusions, which would not have been possible without the advent of highly accurate, genome-wide DNA sequencing of individual human tumor samples. Interestingly, mutations to certain subunits, or particular combinations of mutations in the complex's many subunits, seem to herald the development of specific types of cancer - favoring the development of ovarian versus colon cancer, for example.

The importance of the BAF complex as a tumor suppressor is further emphasized by the fact that, in some cases, a mutation in one subunit is sufficient to initiate cancer development......

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Stanford University Medical Center. (2013, May 8). "Study Shows Protein Complex May Play Role In Preventing Many Forms Of Cancer." Medical News Today. Retrieved from
http://www.medicalnewstoday.com/releases/260128.php