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abstract
Keywords:
- ovarian cancer;
- paraneoplastic cerebellar degeneration;
- paraneoplastic neurological syndrome;
- tacrolimus hydrate;
- Yo antibody
Paraneoplastic
cerebellar degeneration is a paraneoplastic neurological syndrome
caused by the remote effect of certain systemic cancers and is
characterized by subacute cerebellar symptoms. A 62-year-old woman
suffering from unidentified cerebellar symptoms was admitted to our
hospital. Paraneoplastic cerebellar degeneration was suspected and
ovarian cancer was detected after the systemic examination for
malignancy. The symptoms of vertigo and dysarthria were improved a
little after surgical operation and treatments of γ-globulin, steroid
pulse and tacrolimus hydrate. The cerebellar symptoms of paraneoplastic
cerebellar degeneration are often evident prior to detection of
malignancy. It is important to perform systemic examination for
malignancy in case of unidentified cerebellar symptoms.
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