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Blogger's Note: abstract lacks critical detail, pay-per-view for full access
abstract
Highlights
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- The probability of dying from ovarian cancer decreases with time.
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- Ovarian cancer remains the most common cause of death for 15 years after diagnosis in women with stage III–IV tumors.
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- For stage I tumors, ovarian cancer remains the most common cause of death for 6 years after diagnosis.
Objectives
Patients
with solid tumors are at greatest risk for dying from their cancers in
the five years following diagnosis. For most malignancies, deaths from
other chronic diseases begin to exceed those from cancer at some point.
As little is known about the causes of death among long-term survivors
of ovarian cancer, we examined causes of death by years from diagnosis.
Methods
The
Surveillance, Epidemiology, and End Results (SEER) database was used to
identify women diagnosed with ovarian cancer between 1988 and 2012. We
compared causes of death by stage, age, and interval time after
diagnosis.
Results
A total of
67,385 women were identified.
For stage I neoplasms, 13.6% died from ovarian cancer, 4.2% from
cardiovascular disease, 3.6% from other causes and 2.6% from other tumors; ovarian cancer was the leading cause
of death until 7 years after diagnosis after which time deaths are more
frequently due to other causes.
For those with stage III–IV tumors,
67.8% died from ovarian cancer, 2.8% from other causes, 2.3% from cardiovascular disease and
1.9% from other cancers; ovarian cancer was the most
frequent cause of death in years 1–15 after which time deaths were more
commonly due to other causes.
Conclusions
The
probability of dying from ovarian cancer decreases with time. Ovarian
cancer remains the most common cause of death for 15 years after
diagnosis in women with stage III–IV tumors.
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