MRI Imaging Characteristics of Ovarian Clear Cell Carcinoma

Blogger's Note: Table 1 shows signs/symptoms; followup <30 mo; wide variance in CA125's; 8/19 pts = ascites (malignant/non-malignant)

"...CA 125 serum level (normal, < 35 U/mL) was elevated in 17 patients..."

Table 1. Clinical findings of 19 patients with OCCCs

Table 2. MRI characteristics of 21 OCCCs in 19 patients.

open access

"Despite diagnosis at early stages, OCCCs are biologically aggressive neoplasms. The presenting symptoms include abdominal discomfort, pain, distention and gastrointestinal symptoms."

Purpose

To probe the magnetic resonance imaging (MRI) features of ovarian clear cell carcinoma (OCCC).

Methods

This study retrospectively collected MRI data for 21 pathology-confirmed OCCCs from 19 female patients. The MRI findings were analyzed to determine the tumor size, shape/edge, shape and number of protrusions within the cyst, cystic or necrotic components, signal intensity (SI) and enhancement features.

Results

The age of the 19 patients ranged from 28 to 63 years (mean age: 53 years). Unilateral tumors were found in 17 patients (17/19, 89%); the average size of all tumors was 10.8 cm.....