Increasingly Questionable Oncology ‘Outcome’ Data

Clinical Oncology News 
 Increasingly Questionable Oncology ‘Outcome’ Data
Time for a Serious Discussion

Increasingly Questionable Oncology ‘Outcome’ Data

Time for a Serious Discussion

- See more at: http://www.clinicaloncology.com/ViewArticle.aspx?ses=ogst&d=Current+Practice&d_id=155&i=September+2015&i_id=1224&a_id=33509#sthash.0gydzfwZ.dpuf

.....In fact, in a recent provocative paper examining what has been labeled “conditional disease-free survival,” investigators examined the statistical likelihood that an ovarian cancer patient would not have progression of cancer based on the duration of time she had already not exhibited evidence of progression.4 In this analysis, at diagnosis, the probability that an ovarian cancer patient would be disease-free at 5 years was 44.6%. However, if the patient had gone 2 years without experiencing evidence of recurrent disease, the 5-year disease-free survival increased to 80.5%; and if the individual did not exhibit progression for 3 years, the 5-year figure was 92.4%.4 Of course, each of these figures is substantially superior to the baseline recurrence risk of more than 50%.....

In fact, in a recent provocative paper examining what has been labeled “conditional disease-free survival,” investigators examined the statistical likelihood that an ovarian cancer patient would not have progression of cancer based on the duration of time she had already not exhibited evidence of progression.4 In this analysis, at diagnosis, the probability that an ovarian cancer patient would be disease-free at 5 years was 44.6%. However, if the patient had gone 2 years without experiencing evidence of recurrent disease, the 5-year disease-free survival increased to 80.5%; and if the individual did not exhibit progression for 3 years, the 5-year figure was 92.4%.4 Of course, each of these figures is substantially superior to the baseline recurrence risk of more than 50% - See more at: http://www.clinicaloncology.com/ViewArticle.aspx?ses=ogst&d=Current+Practice&d_id=155&i=September+2015&i_id=1224&a_id=33509#sthash.0gydzfwZ.dpuf

In fact, in a recent provocative paper examining what has been labeled “conditional disease-free survival,” investigators examined the statistical likelihood that an ovarian cancer patient would not have progression of cancer based on the duration of time she had already not exhibited evidence of progression.4 In this analysis, at diagnosis, the probability that an ovarian cancer patient would be disease-free at 5 years was 44.6%. However, if the patient had gone 2 years without experiencing evidence of recurrent disease, the 5-year disease-free survival increased to 80.5%; and if the individual did not exhibit progression for 3 years, the 5-year figure was 92.4%.4 Of course, each of these figures is substantially superior to the baseline recurrence risk of more than 50% - See more at: http://www.clinicaloncology.com/ViewArticle.aspx?ses=ogst&d=Current+Practice&d_id=155&i=September+2015&i_id=1224&a_id=33509#sthash.0gydzfwZ.dpuf