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Open access
In conclusion, the present study indicates that in the Chinese population, carriers of the -93AA and AG genotypes have increased risk of ovarian cancer compared with GG carriers. To the best of our knowledge, this study provided the first evidence that the -93G>A polymorphism in hMLH1 is associated with a significant risk of developing ovarian cancer in the Chinese population. Further independent population-based case-control studies are warranted to validate our results in larger sample sizes, as well as in different populations.
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