Fallopian tube organoids promise better understanding of ovarian cancer, infertility

medical news

 A new way of growing fallopian tube cells in culture is expected to give a boost to our understanding and prevention of female genital diseases, such as infertility, inflammatory disease, and ovarian cancer.


Journal Reference:

1. Mirjana Kessler, Karen Hoffmann, Volker Brinkmann, Oliver Thieck, Susan Jackisch, Benjamin Toelle, Hilmar Berger, Hans-Joachim Mollenkopf, Mandy Mangler, Jalid Sehouli, Christina Fotopoulou, Thomas F. Meyer. The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nature Communications, 2015; 6: 8989 DOI: 10.1038/NCOMMS9989