Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

Blog Archives: Nov 2004 - present

#ovariancancers



Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Thursday, December 24, 2015

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers



open access

 Conclusion Age at first breast cancer is a strong risk factor for cumulative CBC risk in BRCA1/2 mutation carriers. Considering the available evidence, age-specific risk estimates should be included in counseling......

 In our unselected cohort of patients with breast cancer , we found 10-year cumulative CBC risks of 21.1% for BRCA1 mutation carriers and 10.8% for BRCA2 mutation carriers, which were two to three times higher than for noncarriers (HR, 3.31 for BRCA1; and HR, 2.17 for BRCA2 mutation carriers).

0 comments :

Post a Comment

Your comments?

Note: Only a member of this blog may post a comment.