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open access
Background
Treatment outcomes appear to be better for ovarian cancer (OC) patients carrying the
BRCA1/2 germline mutation than for patients with sporadic OC. However, most published data
are for North American, British and Jewish populations. There have been very few studies
on treatment outcomes in Central and Eastern European patients with OC. The aim of
this study was to analyse prognostic factors in Polish patients with BRCA1-dependent OC (BRCA1-OC).
Conclusion
Prognostic factors for favourable treatment outcomes in Polish patients with BRCA1-OC do not appear to differ from those in patients with sporadic OC. The incidence
of the endometrial subtype of OC was relatively high (34.9 %) among women in the study.
This was unexpected and has not been reported previously. This subtype of OC was an
independent prognostic factor for favourable treatment outcomes.
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