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Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (LS2) (Lynch Syndrome 2)
Verified July 2015 by University Health Network, Toronto
Sponsor:
University Health Network, Toronto
Collaborators:
Mount Sinai Hospital, Canada
Sunnybrook Health Sciences Centre
Hamilton Health Sciences Corporation
Ryerson University
University of Toronto
Information provided by (Responsible Party):
University Health Network, Toronto
ClinicalTrials.gov Identifier:
NCT02494791
First received: July 7, 2015
Last updated: NA
Last verified: July 2015
History: No changes posted
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This study will maximize identification of women
with Lynch Syndrome using an enhanced screening strategy to identify
those at risk. These women will be referred to genetic counselling for
testing and those found to have Lynch Syndrome will be asked to invite
first degree relatives to participate and undergo genetic testing for
Lynch Syndrome. Screening guidelines and risk reducing surgery options
for participants found to have Lynch Syndrome will be reinforced by the
study and adherence to these guidelines will be assessed annually for
ten years following Lynch Syndrome diagnosis to assess the impact and
cost-effectiveness of this enhanced screening approach.
Condition | Intervention |
---|---|
Lynch Syndrome Endometrial Neoplasms Ovarian Neoplasms Colorectal Neoplasms |
Behavioral: Questionnaire, Educational Material |
Study Type: | Observational |
Study Design: | Time Perspective: Prospective |
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