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abstract
Abstract
Salpingectomy
is the surgical excision of the fallopian tube. Traditionally the tubes
were preserved when undertaking a hysterectomy for benign reasons when
the intention is to conserve the ovaries. Recent evidence from
morphological, embryological, molecular biology and histopathology
points towards the fallopian tube; and in particular the fimbrial end,
being the origin for high-grade serous ovarian cancer. It is advocated
that bilateral salpingo-oopherectomy should be the method of choice for
risk-reducing surgery in patients with high risk of ovarian cancer,
namely those with BRCA1, BRCA2 and mismatch-repair gene
mutations. Increasingly, removal of the fallopian tubes as part of
hysterectomy for benign disease, with preservation of the ovaries, or as
a method for sterilisation in selected groups, has been shown to reduce
the risk of future development of ovarian cancer with minimal adverse
effects on the patient, a process that should be encouraged.
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