open access version: SSRI use and clinical outcomes in epithelial ovarian cancer | Christensen | Oncotarget Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Saturday, April 30, 2016

open access version: SSRI use and clinical outcomes in epithelial ovarian cancer | Christensen | Oncotarget



open access
 
Histology (n) Serous 582 Other 189





Ovarian cancer patients from a 6-site study between 1994 and 2010 were included.
 To date, no studies have examined effects of SSRIs among patients already diagnosed with ovarian cancer and the influence SSRIs may have on survival and disease progression in these patients. Moreover, no studies have explored the effect of 5-HT or SSRIs on ovarian neoplastic cell growth. To address these knowledge gaps, we characterized 5-HT receptor expression in ovarian cancer cells and investigated the functional and biological roles of 5-HT using in vitro and in vivo models. In addition, this multicenter study examined effects of SSRIs on survival and disease progression in patients diagnosed with epithelial ovarian cancer.....


Patient characteristics
Demographic and clinical characteristics of the sample are listed in Table 1
 
 

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