abstract
OBJECTIVES:
To evaluate the outcome of fertility-sparing surgery among young women with early-stage clear cell carcinoma of the ovary.
METHODS:
In
a retrospective study, data were reviewed for patients aged 45years or
younger who had
FIGO stage I clear cell carcinoma of the ovary and had
attended one institution in South Korea between December 1999 and
December 2009. Outcomes were compared between women undergoing
fertility-sparing surgery, defined as preservation of the uterus and at
least one adnexa, and those undergoing radical surgery.
RESULTS:
Overall,
47 patients were included (22 underwent fertility-sparing surgery, 25
radical surgery). After a median follow-up of 72months (range 8-175),
5
(23%) patients who underwent fertility-sparing surgery and 5 (20%) in
the radical surgery group had recurrent disease (P=0.820). The
mean time
to recurrence was 19months after fertility-sparing surgery versus
20months after radical surgery (P=0.935). The anatomical location of
recurrence did not differ. There was no difference in 5-year
disease-free survival (77% vs 84%; P=0.849) or 5-year overall survival
(91% vs 88%; P=0.480).
CONCLUSION:
Fertility-sparing
surgery was found to be a safe alternative for young women with FIGO
stage I clear cell carcinoma of the ovary who wish to preserve
fertility.
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