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Saturday, April 09, 2016

Post-menopausal women taking metformin for diabetes may be at lower risk of cancer



science news

 Date: April 7, 2016
Compared to women without diabetes, women with diabetes had a 13% higher risk of developing invasive cancer. These women also face increased risk that ranges from 20% to nearly double the chances of being diagnosed with the following cancers: colon, liver, pancreas, endometrial and non-Hodgkin lymphoma. Results also show that metformin use was associated with better survival in diabetes patients diagnosed with ovarian, colorectal and breast cancer.
 The researchers say future studies are needed to further clarify the long-term impact of metformin on cancer risk and survival.
 
Journal Reference:
  1. Zhihong Gong, Aaron K. Aragaki, Rowan T. Chlebowski, JoAnn E. Manson, Thomas E. Rohan, Chu Chen, Mara Z. Vitolins, Lesley F. Tinker, Erin S. LeBlanc, Lewis H. Kuller, Lifang Hou, Michael J. LaMonte, Juhua Luo, Jean Wactawski-Wende. Diabetes, metformin and incidence of and death from invasive cancer in postmenopausal women: Results from the women's health initiative. International Journal of Cancer, 2016; 138 (8): 1915 DOI: 10.1002/ijc.29944

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