Estimating cumulative risks for breast cancer for carriers of variants in uncommon genes Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

Blog Archives: Nov 2004 - present

#ovariancancers



Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Tuesday, June 14, 2016

Estimating cumulative risks for breast cancer for carriers of variants in uncommon genes



open access

 Table 1 shows the published risk estimates for specific genes and/or variants within genes. Using the strategy described, this risk is converted to a cumulative risk to age 70 years for carriers living in the USA and other countries with similar population incidences.

Discussion

Establishing penetrance is a difficult proposition, even for extensively studied genes, like BRCA1 and BRCA2, in which no two studies have ever yielded the same results......

0 comments :

Post a Comment

Your comments?