case report: DH1 mutated low grade astrocytoma (brain) occurring in MSH2 mutated Lynch syndrome family Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

Blog Archives: Nov 2004 - present

#ovariancancers



Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Thursday, June 16, 2016

case report: DH1 mutated low grade astrocytoma (brain) occurring in MSH2 mutated Lynch syndrome family



open access (Ontario case report - North York/Sunnybrook)

2. Case and methods

A 72 year old man had a previous diagnosis of colorectal carcinoma and a family history of LS that included: colorectal carcinomas in his father, brother, niece and several paternal aunts and uncles, breast carcinoma and multiple sebaceous adenomas in his sister and ureteric carcinoma and melanoma in his brother. Some family members met criteria for the Muir–Torre variant of LS but our patient did not and no previous family members had a brain tumour/Turcot syndrome. An MSH2 mutation was found in the patient, his niece and sister (560 T $_amp_$gt; C, exon 3).....

0 comments :

Post a Comment

Your comments?