Recurrent Sertoli–Leydig cell tumor of ovary in 8-year-old girl Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Sunday, June 26, 2016

Recurrent Sertoli–Leydig cell tumor of ovary in 8-year-old girl

(Case Report - Turkey)
Sertoli–Leydig cell tumors are rare sex cord-stromal neoplasms that account for <0.2% of ovarian tumors. These tumors with a retiform pattern pose difficult diagnostic problems, with the majority of being misinterpreted as serous papillary cystadenocarcinoma and endodermal sinus tumor. We report an 8-year-old female patient presented to our institution with a huge mass and pain in the lower abdomen and recurrence in the 10th months following the first operation. Only four cases of Sertoli–Leydig cell tumors have been reported under age of the eight years in the literature so far. It is difficult to define the stage and the morphology of Sertoli–Leydig cell tumors with retiform pattern in children and chemotherapy or radiotherapy administration is controversial. However, fertility sparing surgeries should be considered as a first treatment choice on the time of the diagnosis and the recurrence. 


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