The Relevance of Hereditary Cancer Risks to Precision Oncology (mutations/variants...) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Thursday, June 09, 2016

The Relevance of Hereditary Cancer Risks to Precision Oncology (mutations/variants...)



open access:
The Relevance of Hereditary Cancer Risks to Precision Oncology: What Should Providers Consider When Conducting Tumor Genomic Profiling?

 The objectives of this article are to increase awareness among oncologists and cancer care providers that the discovery of hereditary cancer risk as a secondary finding of TGP (ie, a finding indirectly related to the purpose of TGP) is relevant to patient care...
 Table 1 provides a gene-by-gene comparison of the cancer risks associated with carrying a germline mutation, estimates of the prevalence of mutations in these genes in patients with select cancer types (germline mutation prevalence), estimates of prevalence of mutations in these genes in the general population, and the prevalence of somatic (tumor) mutations in these genes in select tumor types.
 eg.(Table 1)