Low-Grade Serous Carcinoma of the Ovary (Cancer Network) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

Blog Archives: Nov 2004 - present


Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Saturday, July 16, 2016

Low-Grade Serous Carcinoma of the Ovary (Cancer Network)

open access


The World Health Organization classification system of ovarian cancer, published in 2014 by Kurman et al, eliminated the older practice of grading serous tumors on a continuum (grade 1, 2, or 3) and instead differentiates low-grade serous and high-grade serous ovarian cancers as two distinct diseases.[1] In general, tumors previously classified as grade 1, and most of those classified as grade 2 according to the old system, are now classified as low-grade serous ovarian cancers (LGSOCs). Those tumors previously classified as grade 3 are now considered high-grade serous ovarian cancers (HGSOCs)....

  • Low-grade serous ovarian cancer is a rare disease, accounting for < 10% of ovarian cancer cases.
  • Initial treatment consists of surgical staging and adjuvant chemotherapy.
  • Recurrent disease is relatively chemoresistant;
    hormonal therapies, as well as bevacizumab and MEK inhibitors, have shown some promising results.


Post a Comment

Your comments?