Major milestones in translational oncology (open access) eg. ovarian biomarker

open access BMC Medicine

Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. Today, translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies regarding the molecular pathways involved in tumorigenesis. In this Forum article, we highlight the state of the art of translational oncology in five major cancer types.

To screen or not to screen for ovarian cancer (OvCa) – results of UKCTOCS study

Vathany Kulasingam and Eleftherios P. Diamandis (Figs. 3 and 4)

 Vathany Kulasingam and Eleftherios P. Diamandis discuss a large, longitudinal United Kingdom screening program for ovarian cancer (OvCa) involving serum measurements of a tumor biomarker, namely carbohydrate antigen 125; although the cost-effectiveness of this program is yet to be defined, the program created a biobank that will support translational research from the clinic back to the laboratory.