Etoposide damages female germ cells in the developing ovary

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Background

Cancer is diagnosed in approximately one out of every 1000 pregnancies, often requiring consideration of chemotherapy administration to the pregnant woman [1, 2, 3, 4]. Chemotherapy administration during the first trimester is now largely avoided, as it is associated with increased risk of congenital malformations and high risk of spontaneous abortion [5]. However.....