Molecular alterations in indolent, aggressive and recurrent ovarian low-grade serous carcinoma Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, August 31, 2016

Molecular alterations in indolent, aggressive and recurrent ovarian low-grade serous carcinoma



Abstract
 

Aims

The clinical course of patients with low-grade serous carcinoma (LGSC) can be substantially different. The purpose of this study was to explore whether molecular or pathological features could identify patients that follow a more aggressive course.

Conclusion

Despite limited case numbers, it appears that current molecular testing is inferior in predicting outcome of LGSCs compared to a pathological parameter or protein expression. Prediction of outcome based on the primary tumour may be confounded by additional acquired changes over time.

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