(calpain inhibitor) Study identifies potential combination therapy for ovarian cancer

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In a comparative analysis, the authors previously described the similarities in the genetic and epigenetic events of breast and ovarian cancer suggesting a common epigenetic origin. They have shown before that combination of histone deacetylase inhibitors with calpain inhibitor produced enhanced growth inhibition and cell death in different types of breast cancer cells including triple negative breast cancer cells as they observed in different types of ovarian cancer cells in this study.